Alterations of bicarbonate HCO3 and carbon dioxide CO2 dissolved in plasma are characteristic of acid-base imbalance. The nature of the imbalance cannot, however, be inferred from the bicarbonate value itself, and the determination of bicarbonate is rarely ordered alone. Its value has significance in the context of other electrolytes determined with it and in screening for electrolyte imbalance. Because the determination of bicarbonate HCO3 actually includes dissolved carbon dioxide CO2 , this fraction will escape from the specimen into the air once the stopper is removed from the vacutainer tube.
If the logistics in the lab are different for processing high-volume routine specimens from STAT specimens, the extent of the error is bicarbonate determinations will be different.
A needle is used to draw blood from a vein in your arm or hand. Having a blood test with a needle carries some risks. These include bleeding, infection, bruising, and feeling lightheaded. When the needle pricks your arm or hand, you may feel a slight sting or pain. Afterward, the site may be sore. Eating acidic fruits could affect your results. Medicines that may raise your levels include:.
You don't need to get ready for this test. Tell your healthcare provider about all medicines, herbs, vitamins, and supplements you are taking. This includes medicines that don't need a prescription and any illegal drugs you may use. Search Encyclopedia. Find more information on the Altmetric Attention Score and how the score is calculated. According to the generally accepted picture of CO 2 dissolution in water, the formation of H 2 CO 3 proceeds in a single step that involves the attack of a water oxygen on the CO 2 carbon in concert with a proton transfer to a CO 2 oxygen.
This alternative scenario was already taken into consideration decades ago, but subsequent experiments and calculations have given preference to the concerted mechanism. Such files may be downloaded by article for research use if there is a public use license linked to the relevant article, that license may permit other uses. B , , 50 , View Author Information. E-mail: [email protected].
Cite this: J. B , , 50 , — Article Views Altmetric -. Citations Supporting Information. Cited By. This article is cited by 66 publications.
The Journal of Physical Chemistry A , 20 , The Journal of Physical Chemistry B , 51 , The Journal of Physical Chemistry Letters , 10 17 , The Journal of Physical Chemistry A , 26 , Miller, David A. Dixon, Sarah D. Burton, Eric D. Walter, David W. Hoyt, Ashley S. McNeill, Joshua D.
Moon, K. Sahan Thanthiriwatte, Eugene S. Ilton, Odeta Qafoku, Christopher J. Thompson, Herbert T. Schaef, Kevin M. Rosso, John S. The Journal of Physical Chemistry C , 20 , The Journal of Physical Chemistry B , 18 , Journal of the American Chemical Society , 14 , The Journal of Physical Chemistry Letters , 9 20 , Haynes, Alejandro Montoya.
Journal of Chemical Theory and Computation , 14 1 , Bicarbonate is a major form of this, being a negatively charged ion which is excreted and reabsorbed by the kidneys. This helps maintain the body's acid-base balance. Bicarbonate also works with the other electrolytes sodium, potassium, and chloride to maintain electrical neutrality at the cellular level. Determination of bicarbonate can be useful in the investigation of acid-base status although assessment is often done by blood gas analysis.
Bicarbonate is decreased in metabolic acidosis e. Artefactual decrease in bicarbonate can occur when samples are delayed in transit or are of small volume due to loss of carbon dioxide into the atmosphere.
0コメント